What's The Difference Between A Juul And A Vape Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: Vapes may seem harmless but can actually expose the body to the same level of nicotine as multiple packs of cigarettes, increasing the risk of dependence without people realizing it. Free resources: Vaping vs Cigarettes Health Impacts Compared How Many Puffs Of A 20mg Vape Is Equal To A Cigarette? (High Equivalency) Comparison of Nicotine Levels Between Cigarettes and Vapes Ecigator A single vape cartridge can have the nicotine equivalent of 600 cigarettes.