How Can I Increase my Wetness Fast? What causes vaginal lubrication? Primarily caused by declining estrogen levels, it can result in discomfort, pain during intercourse, and an increased risk of vaginal infections. Less estrogen results in lower blood flow and lubrication, causing thinning Confused between vaginal moisturizer & lubricant?, This reel breaks it down for you , Save it for later & share with someone who needs this. Arousal, lubrication AND the vestibular glands. The greater and lesser vestibular glands or bartholin and skene glands secrete fluid which provides lubrication. However, this is not the primary source of vaginal lubrication. The Best Vaginal Moisturizers and Creams for Vaginal Dryness