Using lube is a normal and healthy part of being sexually active, but the different options can be daunting. Here's a quick guide to the pros and cons of the most common Jill A quick run down on personal lubricants. . Remember, lubricants are usually used with sex, while vaginal moisturizers are used 2 3 times per week routinely. Some lubricants may also be used Silicone vs. Water Based Lube: Which Works Best for Lasting Intimacy Medicine Mama Silicone Lubricant Spray WD 40 Water Resistant Silicone WD 40 Water Based vs. Silicone: Best Lubricant for Sensitive Skin Sliquid Not all lubes are the same Water, silicone, or oileach one hits different depending on what your body needs. Know the difference, choose what feels good, and let comfort do its